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QLEDs â light-emitting diodes that rely on nanocrystals called quantum dots â are usually made with toxic heavy metals. A strategy has been developed to make QLEDs with a performance comparable to that of commercially available technologies but using a more environmentally friendly alloy of zinc, selenium, telluriu
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The neurons that can put a brake on a nervous-system cancer
3+ day, 13+ hour ago (17+ words) Drugs that imitate the effect of GABAergic neurons slow the growth of tumours called gliomas in mice....
Ketone signaling goes nuclear - Nature Chemical Biology
3+ day, 14+ hour ago (155+ words) Nature Chemical Biology (2026) Cite this article The nucleus is increasingly recognized as a metabolically active hub. A study shows how the ketolytic enzyme OXCT1 translocates to the nucleus to locally deplete β-hydroxybutyrate, suppressing anti-tumor immunity through site-specific epigenetic remodeling. van der…...
Biotech news from around the world - Nature Biotechnology
3+ day, 17+ hour ago (240+ words) Biotech news from around the world Nature Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or…...
Response to comment on: cardiovascular and prostate cancer risk associated with testosterone replacement therapyâa systematic review and meta-analysis of 41 randomized controlled trials | International Journal of Impotence Research
3+ day, 19+ hour ago (196+ words) International Journal of Impotence Research (2026) Cite this article All data analyzed or generated during the development of this study are included in this published article and its supplementary data file. Goligher EC, Heath A, Harhay MO. Bayesian statistics for clinical…...
Pharmaceutical products with device-only patents: a cross-sectional analysis - Nature Biotechnology
3+ day, 17+ hour ago (360+ words) The FDA cannot approve generic drugs for marketing until brand-name drug patents on its list expire or are successfully challenged, but courts have recently found that certain device-only patents are impermissible and should not be listed. Teva Branded Pharm. Prods....
ATP-independent unfolding of ubiquitin by Ufd1 initiates Cdc48/p97-mediated substrate processing | Nature Structural & Molecular Biology
4+ day, 1+ hour ago (1569+ words) Nature Structural & Molecular Biology (2026) Cite this article Coordinates and structure files were deposited to the Protein Data Bank under accession code PDB 22ID (ctUT3–C19). Any additional information required to reanalyze the data reported in this paper is available upon request. Source data…...
Dendritic cells sense microbial adhesion to launch innate immunity - Nature Immunology
4+ day, 21+ min ago (257+ words) Nature Immunology (2026) Cite this article In a mouse skin infection model, microbial adhesion to CD11c+ myeloid cells activates PIEZO1 and an LTB4–IL-1α–CXCL1 cascade that recruits neutrophils before Toll-like receptor signaling becomes dominant. These findings identify a first phase of innate immune defense…...
Applying the FDA’s plausible mechanism guidance across the rare disease landscape - Nature Genetics
4+ day, 15+ hour ago (191+ words) Nature Genetics (2026) Cite this article In February 2026, the FDA published a draft guidance establishing a plausible mechanism framework for individualized therapies that target rare genetic diseases. The framework is a genuine advance, but its five criteria are not equally tractable,…...
A guide to understanding tumour evolution through the lens of population genetics - Nature Reviews Cancer
4+ day, 16+ hour ago (1645+ words) Nature Reviews Cancer (2026) Cite this article Greaves, M. & Maley, C. C. Clonal evolution in cancer. Nature 481, 306–313 (2012). This landmark review outlines the fundamental principles of cancer evolution. Marusyk, A., Almendro, V. & Polyak, K. Intra-tumour heterogeneity: a looking glass for cancer? Nat. Rev. Cancer 12, 323–334 (2012). McGranahan,…...
AI model predicts which breast-cancer drugs work best
4+ day, 17+ hour ago (277+ words) Model trained on millions of protein measurements can gauge drug effectiveness in tissue samples taken from people with triple-negative breast cancer....